王书珍，女，武汉大学理学博士，教授，1984.07，河南郑州人，兼任山东中医药大学硕士生导师、长江大学硕士生导师、黄冈师范学院学科教学（生物）硕士生导师。湖北省首批“优秀基层组织”负责人（生物科学教研室），湖北省一流课程《专业认知与劳动实践》课程负责人。黄冈市最美科技工作者。学校第一届“明珠学者”人才、年度校园风云人物、校第一届“最美一线教师”、“明珠巾英”。主讲《生物化学》、《生物科学专业导论与职业规划》、《花艺与生活》、《药食同源与营养健康》等课程。
目前主要从事杜鹃花的遗传改良和种质创新研究，以及大别山特色中草药资源的生物学功能研究和分子育种研究。主持国家自然科学基金项目、湖北省科技厅自然科学基金、湖北省教育厅青年基金、湖北省知识产权局基金、黄冈市科技计划项目、经济林木湖北省重点实验室项目多项，参与国家“863”研究计划。在《Food & Function》、《Food Science and Human Wellness》、《Gene》、《Breeding Science》、《Euhpytica》等杂志公开发表学术论文60余篇，其中SCI论文40余篇，获批发明专利5项，参编《基因工程》、《简明生物化学》、《食用农产品资源与健康》、《大别山中药材栽培与加工技术》等多部。
一、代表性科研项目
1.国家自然科学基金青年基金, 31500995、基于SSR标记的大别山野生杜鹃花资源遗传多样性研究、2016/01-2018/12、26.4万、主持、结题。
2.湖北省科技厅自然科学基金项目, 2021CFB320、大别山映山红花色形成关键miRNA挖掘及功能分析、8万、2021/09-2023/12、主持。
3、湖北省自然科学基金, 2015CFC816、生菜品质性状相关EST-SSR标记的筛选及应用潜力研究、2015/01-2017/12、主持、结题。
4、湖北省教育厅科学技术研究重点项目, D20222902、基于基因组学的映山红种质资源多样性与进化研究、2022/01-2024/12、4万、主持、在研。
5、湖北省教育厅科学技术研究项目, Q20152903、湖北龟峰山杜鹃花种质资源遗传多样性研究、2015/01-2016/12、1.5万、主持、结题。
6. 湖北省知识产权局项目, 大别山杜鹃花新品培育及良种快繁体系建立、2019025, 2019.01-2021.12、主持、结题。
7. 黄冈市科技局研究项目，大别山黄精良种繁育及药食同源新产品研发、ZDXM20220023，2022.9-2023.9、主持。
二、代表性论文
1. Shuzhen Wang, Fe He, Hongmei Wu, Fu Xiang, Hongyan Zheng, Wei Wu, Shiming Li. Health-Promoting Activities and Associated Mechanisms of Polygonati Rhizoma Polysaccharides. Molecules, 2023, 28(3):1350.
2. Bo Fang, Zhiwei Huang, Yirong Sun, Wanjing Zhang, Jiaojun Yu, Jialiang Zhang, Hongjin Dong, Shuzhen Wang*(通讯). Small RNA sequencing provides insights into molecular mechanism of flower development in Rhododendron pulchrum Sweet. Sci Rep. 2023,13(1): 17912.
3. Zhiliang Li, Zhiwei Huang, Xuchun Wan, Jiaojun Yu, Hongjin Dong, Jialiang Zhang, Chunyu Zhang, Shuzhen Wang*(通讯). Complete chloroplast genome sequence of Rhododendronmariesii and comparative genomics of related species in the family Ericaeae. Comp Cytogenet. 2023, 17: 163-180.
4. Bilin Xu＃, Zhiliang Li＃, Yan Liu, Wanjing Zhang, Jiaojun Yu, Hongjin Dong, Jialiang Zhang, Shuzhen Wang*(通讯). Complete chloroplast genome sequence and phylogenetic analysis ofrhododendron molleg. don, an endangered ericaceae species located on dabie mountains (central china). Plant Biotechnology Reports, 2023, 17(2): 303-314.
5. Yunli Xiao, Wanjing Zhang, Yirong Sun, Zhiliang Li, Jiaojun Yu, Chunyu Zhang, Shuzhen Wang*(通讯). The complete chloroplast genome sequence of Rhododendron fortunei: Structural comparative and phylogenetic analysis in the ericaceae family. Botanica Serbica, 2023,47(2): 279-290.
6. Shuzhen Wang, Ting Zeng, Shuang Zhao, Yu Zhu, Changchun Feng, Jianfeng Zhan, Shiming Li, Chi-Tang Ho, Alexander Gosslau. Multifunctional health-promoting effects of oolong tea and its products. Food Science and Human Wellness, 2022, 11, 512-523.
7. Zhiliang Li, Changchun Feng, Hongjin Dong, Weibin Jin, Wenying Zhang, Jianfeng Zhan*, Shuzhen Wang*(通讯). Health promoting activities and corresponding mechanisms of (-)-Epicatechin -3-gallate. Food Science and Human Wellness, 2022, 11, 568-578.
8. Shuzhen Wang, QianLiu,TingZeng, Jianfeng Zhan,Hui Zhao, Chi-Tang Ho, Yunli Xiao, Shiming Li*. Immunomodulatory effects and associated mechanisms of Momordica charantia and its phytochemicals. Food and Function, 2022,13(23): 11986-11998.
9. Shuzhen Wang, Shiying Huang, Jie Yang, Zhiliang Li, Mingju Zhang, Yuanping Fang, Qiaofeng Yang*, Weibin Jin*. Metabolite profiling of violet, white and pink flowers revealing flavonoids composition patterns in Rhododendron pulchrum Sweet. Journal of Biosciences, 2021, 46(1): 3.
10. Zhiliang Li, Qiaofeng Yang, Xue Dong, Yu Zhu, Shuang Zhao, Wenying Zhang, Shuzhen Wang*. Transcriptome analysis of flower color variation in five Rhododendron species (Ericaceae). Brazilian Journal of Botany, 2021, 44(3): 685-695.
11. Shuzhen Wang, Zhiliang Li, Yuting Ma, Yan Liu, Chi-Chen Lin, Shiming Li, Jianfeng Zhan, Chi-Tang Ho. Immunomodulatory Effects of Green Tea Polyphenols. Molecules, 2021, 26: 3755.
12. Linchuan Fang, Jing Mao, Dongyun Xu, Yanfang Dong, Yuan Zhou, Shuzhen Wang*. Development of high quality EST-SSR markers in Rhododendron obtusum Hort. ex Wats. and their use in determining relationships among Rhododendron cultivars. Genetic Resources and Crop Evolution, 2021, 1-14.
13. Shuzhen Wang, Zhiliang Li, Yanyan Luo, Zhengqiang Jin, Weibin Jin, Jun Xiang, Yuanping Fang*. Genetic diversity of Rhododendron simsii Planch. natural populations at different altitudes in Wujiashan Mountain (central China). Caryologia, 2019, 72(3): 41-51.
14. Shuzhen Wang, Zhenqiang Jin, Xudong Guo, Zhiliang Li, Jun Xiang, Weibin Jin*. Genetic diversity and population structure of Rhododendron simsii Planch. (Ericaceae) populations based on microsatellite markers. Nordic Journal of Botany, 2019, 37(4):1-10
15. Wang Shuzhen, Li Zhiliang, Jin Weibin, Fang Yuanping, Yang Qiaofeng, Xiang Jun*. Transcriptome analysis and identification of genes associated with flower development in Rhododendron pulchrum Sweet (Ericaceae). Gene. 2018, 679:108-118.
16. Wang Shuzhen, Li Zhiliang, Guo Xudong, Fang Yuanping, Xiang Jun, Jin Weibin*. Comparative analysis of microsatellite, SNP, and InDel markers in four Rhododendron species based on RNA-seq. Breeding science, 2018, 68(5): 536-544.
17. Wang Shuzhen, Li Zhiliang, Jin Weibin, Xiang Fu, Xiang Jun, Fang Yuanping*. Development and characterization of polymorphic microsatellite markers in Rhododendron simsii (Ericaceae). Plant Species Biology, 2017, 32(1): 100-103.
18. Wang Shuzhen, Li Zhiliang, Yang Guliang, Ho Chitang, Li Shiming*. Momordica charantia: a popular health-promoting vegetable with multifunctionality. Food & Function, 2017, 8(5): 1749 -1762.
19. Wang Shuzhen, Zhou Guolin, Huang Xingxue, Hu Jihong, Wang Bincai, Lin Chufa, Li Xia, Jia Yongpeng, Wang Aihua. Transcriptome analysis of non-heading Chinese cabbage under heat stress by RNA-seq and marker identification. Euhpytica, 2017, 213(5): 109.
20. Wang Shuzhen, Wang Bincai, Liu Jie, Ren Jin, Huang Xingxue, Zhou Guolin, Wang Aihua*. Novel polymorphic EST-based microsatellite markers characterized in lettuce (Lactuca sativa). Biologia, 2017, 72(11): 1300-1305.
21. Wang Shuzhen, Zhang Hongyuan, Zheng Yinzhen, Li Zhiliang, Xiang Fu, Ding Yi*, Xiang Jun*. Environmental factors and phytohormones enhancing expressionof α-momorcharin gene in Momordica charantia. Biologia, 2016, 71(2): 155-160.
22. Wang Shuzhen, Zheng Yongliang, Xiang Fu, Li Shiming, Yang Guliang*. Antifungal activity of Momordica charantia seed extracts toward the pathogenic fungus Fusarium solani L. Journal of Food & Drug Analysis, 2016, 24(4), 881-887.
23. Wang Shuzhen, Li Zhiliang, Li Shiming, Di Rong*, Ho Chitang, Yang Guliang*. Ribosome-inactivating proteins (RIPs) and their important health promoting property. Rsc Advances, 2016, 6(52): 46794-46805.
24. Yang Guliang, Li Shiming*, Wang Shuzhen*. Research progress in enzyme activity and pharmacological effects of ribosome-inactivity protein in bitter melon. Toxin Reviews, 2016, 35(3): 1-5.
25. Wang Shuzhen, Zheng Yinzhen, Yan Junjie, Zhu Zhixuan, Wu Zhihua, Ding Yi*. Alpha-momorcharin, a ribosome-inactivating protein from Momordica charantia, possessing DNA cleavage properties. Protein and peptide letters, 2013, 20(11): 1257-1263.
26. Wang Shuzhen, Zhang Yubo, Liu Honggao, He Ying, Yan Junjie, Wu Zhihua, Ding Yi*. Molecular cloning and functional analysis of a recombinant ribosome- inactivating protein (alpha-momorcharin) from Momordica charantia. Applied Microbiology and Biotechnology, 2012, 96(4): 939 -950.
27. Wang Shuzhen, Pan Lei, Hu Kan, Chen Chanyou, Ding Yi*. Development and characterization of polymorphic microsatellite markers in Momordica charantia (Cucurbitaceae). American Journal of Botany, 2010, 97(8): e75-e78.
28.Yang Guliang, Li Shiming*, Wang Shuzhen*. Research progress in enzyme activity and pharmacological effects of ribosome-inactivity protein in bitter melon. Toxin Reviews, 2016, 35(3): 1-5.
29. 杨谷良, 李士明*, 王书珍*. 苦瓜核糖体失活蛋白生物活性与功能研究进展. 食品科学, 2016, 37(13): 226 -231.
30. 王书珍, 张羽佳, 黄诗颖, 罗炎炎, 金正强, 李志良, 金卫斌. 基于锦绣杜鹃花蕾转录组的 SSR标记开发及应用. 林业科学研究, 2019, 32(3): 97-104.
31. 张羽佳, 舒读, 董雪, 杜睿琛, 李志良, 王书珍*. 大别山黄杜鹃根茎叶花内参基因的表达稳定性评价. 分子植物育种，2020, 18(21): 6963-6968.
32. 王书珍, 张霖, 杨雯, 罗滢, 郑壮, 方元平, 项俊，金卫斌. 大别山不同龄级映山红种群遗传多样性的ssr分析. 林业科学研究, 2018, 31(5), 125-130.
33. 王书珍, 王斌才, 黄兴学, 李志良, 周国林, 汪爱华. 生菜资源表型性状变异及其与SSR标记的关联分析. 北方园艺, 2018, (05): 1-6.
34. 张蓓林, 李志良, 方姣, 郭旭栋, 干建平, 王书珍*. 不同坡向映山红种群遗传多样性的ISSR研究. 北方园艺, 2018, (14): 97-101.
35. 张蓓林, 任瑾, 田时雨, 李志良, 干建平, 王书珍*. 大别山地区杜鹃花资源遗传多样性的ISSR分析. 北方园艺, 2018, (24): 79-84.
三、发明专利
1.王书珍, 李志良, 金卫斌, 张明菊, 胡雨晴, 杜睿琛. 基于转录组测序开发的黄杜鹃SSR引物对及筛选方法与应用. 专利号: ZL 2018 1 1560600.8, 2021授权.
2. 王书珍, 李志良, 金卫斌, 张明菊, 邓玉林, 程洪.基于转录组测序开发的满山红SSR引物对及筛选方法与应用. 专利号: ZL 2018 1 1561351.4, 2021授权.
3. 王书珍,金卫斌,张明菊,李志良,夏奥蕾,张羽佳, 黄诗颖. 基于转录组测序开发的云锦杜鹃SSR引物对及筛选方法与应用. 专利号: ZL 2018 1 1567446.7,2021授权.
4. 王书珍，李志良，金卫斌，张明菊，郭旭栋，胡雨晴，夏奥蕾. 锦绣杜鹃EST-SSR标记开发及应用. 专利号：2018 1 1562780.3, 2021授权.
5. 王书珍等.一种基于杜鹃花转录组数据的SSR分子标记引物及其筛选方法与应用. 专利号：ZL201610564377.9, 2018授权.
四、指导学生获奖
1. 2020年，第六届全国师范院校师范生教学技能竞赛指导教师奖，全国竞赛一等奖，田家炳基金会；
2. 2015、2018、2020年，湖北省大学生“挑战杯”指导教师奖，湖北省教育厅；
3. 2017、2019、2020年，全国大学生生命科学创新创业大赛指导教师奖，教育部高等学校生物技术、生物工程类专业教学指导委员会；
4. 2018、2019、2020年，湖北省大学生生物实验技能竞赛指导教师奖，湖北省教育厅；
5. 2015、2016、2017、2018、2019年，“华文杯”全国师范生生物教学能力测试、生物教学设计能力测试指导教师奖，中国教育技术协会。